What is the importance of identifying and addressing microvascular disease, and specifically microvascular obstruction in heart attack patients?

What is coronary microvasculature?

The coronary microcirculation plays a critical role in the heart’s blood flow regulation and is defined as vessels with a lumen diameter of <400 μm.
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What is a microvascular obstruction (MVO)?

Microvascular Obstruction (MVO) is a frequent complication (up to 60 % in acute heart attack patients) which happens when small blood vessels in the heart become blocked, leading to tissue death.
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How is MVO measured and detected today?

The gold standard for MVO detection is cardiac magnetic resonance (CMRI), which is not routinely utilized and is not performed early in the management of acute heart attack patients.
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What happens if MVO is not detected or treated?

Up to 20 % of treated heart attack patients are re-hospitalized with heart failure (HF) or other major adverse cardiac events. MVO is seen as the most powerful prognostic indicator for these adverse outcomes.
Learn more

What is the importance of identifying and addressing microvascular disease, and specifically microvascular obstruction in heart attack patients?

What is coronary microvasculature?

The coronary microcirculation plays a critical role in the heart’s blood flow regulation and is defined as vessels with a lumen diameter of <400 μm.
Learn More

What is a microvascular obstruction (MVO)?

Microvascular Obstruction (MVO) is a frequent complication (up to 60 % in acute heart attack patients) which happens when small blood vessels in the heart become blocked, leading to tissue death.
Learn More

How is MVO measured and detected today?

The gold standard for MVO detection is cardiac magnetic resonance (CMRI), which is not routinely utilized and is not performed early in the management of acute heart attack patients.
Learn More

What happens if MVO is not detected or treated?

Up to 20 % of treated heart attack patients are re-hospitalized with heart failure (HF) or other major adverse cardiac events. MVO is seen as the most powerful prognostic indicator for these adverse outcomes.
Learn more

The CorFlow Controlled Flow Infusion (CoFI) System

*MOCA I and US pivotal MOCA II data pending. Investigational device use only.

The CoFI System has been created by physicians for physicians, to change the paradigm of diagnosis and treatment of heart attack patients. It is a singular innovation, years in the making — rooted firmly in sound research, from benchtop science to clinical use in humans. The development goals include improving cardiac patient outcomes, expanding physician treatment capabilities, and reducing inequalities to receive state-of-the-art care.

The CorFlow Controlled Flow Infusion (CoFI™) System

*MOCA I and US pivotal MOCA II data pending. Investigational device use only.

The CoFI System has been created by physicians for physicians, to change the paradigm of diagnosis and treatment of heart attack patients. It is a singular innovation, years in the making — rooted firmly in sound research, from benchtop science to clinical use in humans. The development goals include improving cardiac patient outcomes, expanding physician treatment capabilities, and reducing inequalities to receive state-of-the-art care.

Our Vision ?

To be the leader in diagnostic and therapeutic solutions for restoring healthy microvascular blood flow anywhere in the human body where a critical need exists.

Our Vision ?

To be the leader in diagnostic and therapeutic solutions for restoring healthy microvascular blood flow anywhere in the human body where a critical need exists.

CorFlow is developing a medical device that will be the first to diagnose MVO in real-time during PCI and serve as a treatment platform in the cath lab.

Who we are
Our Office

The CoFI-System is not approved in the United States of America.  It is an investigational device limited by federal law to investigational use and is not available for commercial distribution.

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